trenbolone enanthate

Once inside it absorbed about 75%. Clinical effects occur in half an hour after administration and the maximum concentration  reached after 2 hours, the equilibrium concentration achieved at constant reception 1-2 weeks.Diazepam operates for a long time.

Trenbolone enanthate to plasma proteins is 94-99%, and usually higher in men than in women. Diazepam and its metabolites penetrate the blood-brain barrier (BBB) and placental barriers found in human milk in concentrations corresponding to the concentrations of 10.1 parts of in plasma. Relationship to plasma proteins -. 98% is metabolized in the liver of 98-99% to the pharmacologically active derivatives (desmetildiazepam) or less active (temazepam and oxazepam). Excreted by the kidneys – 70% (in the form of glucuronides), in an unmodified form – 1-2% and less than 10% – the faeces. The half-life (T 1/2 ) desmetildiazepama – 30-100 hours, temazepam – 9.5 -12.4 hours and oxazepam -. 5-15 hours T 1/2 can be prolonged in the newborn (30 hours), and elderly patients old age (up to 100 hours) and in patients with hepatic and renal failure (up to 4 days). If you re-use the accumulation of diazepam and its active metabolites significant. It refers to benzodiazepines with a long T 1/2 , removing a slowly after stopping treatment, asmetabolites retained in blood for several days or even weeks.

 

Indications for use
Treatment of neurosis and neurotic disorders with anxiety manifestation.
In the treatment of agitation associated with anxiety.
In the treatment of epileptic trenbolone enanthate seizures and convulsions of various etiologies. Apply with conditions accompanied by increased muscle tone (tetanus, acute cerebrovascular accident).
In the treatment of abstinence syndrome in alcoholism.
It is also used for sedation and ataralgezii combined with analgesics and other neurotropic agents in various diagnostic procedures, surgical and obstetric practice.
in the clinic of internal diseases:. in the treatment of hypertensive disease (accompanied by anxiety, irritability), hypertensive crisis, vascular spasms, menopausal and menstrual disorders
. The disease Mepera
in dermatological practice used in pruritic dermatoses.
insomnia (difficulty falling asleep).

 

Contraindications:

Increased sensitivity to benzodiazepines, severe myasthenia gravis, coma, shock, angle-closure glaucoma, the phenomenon of addiction in history (drugs, alcohol, except for the treatment of alcohol withdrawal syndrome and delirium), sleep apnea trenbolone enanthate┬ásyndrome, a state of acute alcoholic intoxication with depression of vital functions, acute intoxication of drugs, have a depressing effect on the central nervous system (narcotics, sleeping pills and psychotropic drugs), severe chronic obstructive pulmonary disease (risk of progression of respiratory failure), acute respiratory failure, children under 6 years of age, pregnancy (especially 1 trimester), thoracic feeding. Precautions – absence (petit mal) or Lennox-Gastaut syndrome; epilepsy, liver and / or kidney failure, cerebral and spinal ataxia, hyperkinesis, a tendency to abuse of psychotropic drugs, organic brain disease (possible paradoxical reactions), hypoproteinemia, old age, depression (see. “Special Instructions”).

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